A small dose of hydrogen peroxide enhances tumor necrosis factor-alpha toxicity in inducing human vascular endothelial cell apoptosis: Reversal with propofol

Published on Jul 1, 2006in Anesthesia & Analgesia3.489
· DOI :10.1213/01.ane.0000221183.02244.80
Tao Luo45
Estimated H-index: 45
Zhengyuan Xia32
Estimated H-index: 32
We designed the present study to test the hypothesis that oxygen free radicals can enhance tumor necrosis factor (TNF)-α cellular toxicity, which might be reversed by propofol, an anesthetic with antioxidant properties, in human vascular endothelial cell line ECV304. Cultured ECV304 were either not
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