Current trends in α‐helical membrane protein crystallization: An update

Volume: 21, Issue: 9, Pages: 1358 - 1365
Published: Aug 10, 2012
Abstract
α-Helical membrane proteins (MPs) are the targets for many pharmaceutical drugs and play important roles in human physiology. In recent years, significant progress has been made in determining their atomic structure using X-ray crystallography. However, a major bottleneck in MP crystallography still remains, namely, the identification of conditions that give crystals that are suitable for structural determination. In 2008, we undertook an...
Paper Details
Title
Current trends in α‐helical membrane protein crystallization: An update
Published Date
Aug 10, 2012
Volume
21
Issue
9
Pages
1358 - 1365
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