Temporal expression of AMP-activated protein kinase activation during the kainic acid-induced hippocampal cell death

Volume: 116, Issue: 1, Pages: 33 - 40
Published: Jan 1, 2009
Abstract
Kainic acid (KA)-induced seizure induces the hippocampal cell death. There are reports that AMP-activated protein kinase (AMPK), which is an important regulator of energy homeostasis of cells, has been proposed as apoptotic molecule. In this study, we investigated the altered expression of AMPK cascade in the hippocampus of mice during KA-induced hippocampal cell death. Mice were killed at 2, 6, 24 or 48 h after KA (30 mg/kg) injection....
Paper Details
Title
Temporal expression of AMP-activated protein kinase activation during the kainic acid-induced hippocampal cell death
Published Date
Jan 1, 2009
Volume
116
Issue
1
Pages
33 - 40
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