Dermal hypersensitivity reaction as a prodrome to Hodgkin lymphoma

To the Editor: The definition of dermal hypersensitivity reaction (DHR) as a histopathologic diagnosis with a specific clinical correlate is poorly established. Clinical entities often associated with this histologic pattern vary widely: urticaria, drug reactions, arthropod bite reactions (papular urticaria), spongiotic (eczematous) dermatitis, reactions associated with systemic malignancy, pruritic urticarial papules and plaques of pregnancy,...