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References86
Newest
Published on Jan 1, 2012in Medicine1.87
Arezou Khosroshahi25
Estimated H-index: 25
,
Mollie N. Carruthers15
Estimated H-index: 15
+ 3 AuthorsJohn H. Stone67
Estimated H-index: 67
AbstractPatients with IgG4-related disease (IgG4-RD) typically have elevated serum concentrations of IgG4 and share histopathologic features that are similar across affected organ(s). IgG4-RD patients frequently require prolonged treatment with glucocorticoids and are often unable to taper these med
Published on Nov 1, 2011in Radiology7.61
Dai Inoue16
Estimated H-index: 16
,
Yoh Zen62
Estimated H-index: 62
+ 6 AuthorsOsamu Matsui52
Estimated H-index: 52
Immunoglobulin G4 (IgG4)-related arterial lesions occur mainly in the aorta and its main branches and are radiologically characterized by homogeneous arterial wall thickening and enhancement at late phase contrast-enhanced CT, which represent histological features of IgG4-related sclerosing inflammation predominantly involving the adventitia.
Published on Jul 6, 2011in Journal of the American Chemical Society14.70
Theo Rispens33
Estimated H-index: 33
,
Pleuni Ooijevaar-de Heer9
Estimated H-index: 9
+ 1 AuthorsRob C. Aalberse57
Estimated H-index: 57
Immunoglobulin G (IgG) antibodies are symmetrical molecules that may be regarded as covalent dimers of 2 half-molecules, each consisting of a light chain and a heavy chain. Human IgG4 is an unusually dynamic antibody, with half-molecule exchange (“Fab-arm exchange”) resulting in asymmetrical, bispecific antibodies with two different antigen binding sites, which contributes to its anti-inflammatory activity. The mechanism of this process is unknown. To elucidate the elementary steps of this inter...
Published on Jul 1, 2011in Journal of The American Society of Nephrology8.55
Yassaman Raissian5
Estimated H-index: 5
(Mayo Clinic),
Samih H. Nasr45
Estimated H-index: 45
+ 10 AuthorsSuresh T. Chari73
Estimated H-index: 73
IgG4-related systemic disease is an autoimmune disease that was first recognized in the pancreas but also affects other organs. This disease may manifest as tubulointerstitial nephritis (IgG4-TIN), but its clinicopathologic features in the kidney are not well described. Of the 35 patients with IgG4-TIN whose renal tissue specimens we examined, 27 (77%) had acute or progressive chronic renal failure, 29 (83%) had involvement of other organ systems, and 18 of 23 (78%) had radiographic abnormalitie...
Published on Mar 1, 2011in Journal of Clinical Pathology2.35
Johanna Strehl11
Estimated H-index: 11
,
Arndt Hartmann72
Estimated H-index: 72
,
Abbas Agaimy35
Estimated H-index: 35
Background IgG4-related systemic fibrosclerosis is a recently defined disorder characterised by a diffuse or tumefactive inflammatory reaction rich in IgG4-positive plasma cells associated with sclerosis and obliterative phlebitis. Although characteristic histopathological features are essential for the diagnosis of these disorders, to date there exists no consensus regarding the cut-off values used to define a ‘significant IgG4-positive plasma cell count,’ and data regarding the distribution of...
Published on Jan 1, 2011in Current Opinion in Rheumatology3.85
Arezou Khosroshahi25
Estimated H-index: 25
,
John H. Stone67
Estimated H-index: 67
Published on Jan 1, 2011in Current Opinion in Rheumatology3.85
Ajay Nirula1
Estimated H-index: 1
,
Scott M Glaser1
Estimated H-index: 1
+ 1 AuthorsFrederick R Taylora1
Estimated H-index: 1
Purpose of reviewRecent descriptions of the group of clinical disorders collectively defined as IgG4-related systemic disease (IgG4-RSD) have prompted this review of the unique biology of the IgG4 antibody. This article will discuss IgG4 structure and function, the unique phenomenon of half-antibody
Published on Jan 1, 2011in The American Journal of Surgical Pathology6.16
Vikram V. Deshpande85
Estimated H-index: 85
(Harvard University),
Rajib Gupta5
Estimated H-index: 5
(Harvard University)
+ 6 AuthorsGregory Y. Lauwers85
Estimated H-index: 85
(Harvard University)
Autoimmune pancreatitis (AIP) is a chronic inflammatory disease of the pancreas. Examination of pancreatic resection specimens from patients with AIP has shown that there are 2 subclasses of this disease. However, there is no widely accepted pathologic classification scheme and the clinical significance of such a classification remains to be established. In this study, we revisited the subclassification of AIP and examine whether this provides clinically and prognostically meaningful information...
Published on Jan 1, 2011in Current Opinion in Rheumatology3.85
Raghuwansh P. Sah17
Estimated H-index: 17
(Mayo Clinic),
Suresh T. Chari73
Estimated H-index: 73
Purpose of review IgG4-related systemic disease (ISD) is a recently recognized syndrome affecting multiple organs. Autoimmune pancreatitis (AIP) is the pancreatic manifestation of ISD and mimics pancreatic cancer. Current data show frequent association with serum IgG4 elevation and other serologic abnormalities. Here we explore the diagnostic and possible prognostic utility and pathogenetic implications of serologic abnormalities in ISD. Recent findings Serum IgG4 elevations (>140 mg/dl) are see...
Published on Dec 1, 2010in Journal of Clinical Pathology2.35
Yasuharu Sato26
Estimated H-index: 26
(RMIT: RMIT University),
Masaru Kojima1
Estimated H-index: 1
(Dokkyo Medical University)
+ 7 AuthorsTadashi Yoshino58
Estimated H-index: 58
(Okayama University)
Background Differentiation between multicentric Castleman9s disease and systemic immunoglobulin (Ig) G4-related lymphadenopathy is sometimes difficult. It has been suggested that measurement of the IgG4-/IgG-positive cell ratio is useful for the differential diagnosis of the two diseases. However, the authors present a detailed report of six patients with multicentric Castleman9s disease with abundant IgG4-positive cells (IgG4-/IgG-positive cell ratio, >40%). Results In the present series, the p...
Cited By1253
Newest
Published on 2020in Internal Medicine0.96
Naoya Yasokawa , Ryo Shirai14
Estimated H-index: 14
+ 3 AuthorsMikio Oka26
Estimated H-index: 26
Published on Jan 1, 2020
Giorgio Trivioli1
Estimated H-index: 1
,
A. Vaglio2
Estimated H-index: 2
ANCA-associated vasculitides (AAVs) are small-vessel vasculitides with a broad spectrum of manifestations, since almost all organs can be affected. Miscellaneous organ manifestations including the involvement of cardiovascular and musculoskeletal system, gastrointestinal and urogenital tract, occur in only a minority of patients but may have a profound impact on morbidity and mortality. As an example, cardiac involvement, including subclinical forms, is emerging as a diffuse and insidious diseas...
Published on Jan 16, 2019in BMC Nephrology2.09
Shen-Ju Gou (Sichuan University), Lu-Jia Xue (Sichuan University), Zhangxue Hu3
Estimated H-index: 3
(Sichuan University)
Understanding the uncommon association of IgG4-related disease with other disorders is essential for the accurate diagnosis and effective treatment of patients. To the best of our knowledge, there have been only few reports of patients with IgG4-related kidney disease coexisting with metastasis of malignancy. Here, we report a rare case of simultaneous occurring IgG4-related tubulointerstitial nephritis and colon adenocarcinoma with hepatic metastasis. A 71-year-old Chinese man presented with dy...
Published on Feb 1, 2019in Arthritis Research & Therapy4.15
Mu Wang2
Estimated H-index: 2
(Peking Union Medical College Hospital),
Panpan Zhang3
Estimated H-index: 3
(Peking Union Medical College Hospital)
+ 15 AuthorsXiaofeng Zeng18
Estimated H-index: 18
(Peking Union Medical College Hospital)
Background This study aimed to compare the differences and similarities in the clinical manifestations and treatment efficacy of IgG4-related disease (IgG4-RD) in patients with and without dacryoadenitis and sialoadenitis (DS).
Published on Feb 6, 2019in Insights Into Imaging
Daniel Lyndon , Joseph A. Lansley1
Estimated H-index: 1
+ 1 AuthorsAnant S. Krishnan1
Estimated H-index: 1
Meningiomas are the most common dural tumour. They are regularly being seen as an incidental finding on brain imaging and treated conservatively. However, there are many other dural masses which mimic their appearances, including primary neoplastic processes, metastases, granulomatous diseases and infection. While some of these are rare, others such as metastases and tuberculosis arise relatively frequently in practice. Although not pathognomonic, key features which increase the probability of a...
Published on Dec 1, 2019in BMC Surgery1.77
Jiayu Shen (Sichuan University), Yang Zhou + 1 AuthorsJia Hu6
Estimated H-index: 6
(Sichuan University)
The combination of multiple giant coronary artery aneurysms (CAAs) and right coronary artery (RCA) to pulmonary artery (PA) fistula is extremely rare and the patients with CAAs may suffer from several fatal complications. We herein describe a 60-year-old female with hemodynamic instability who was diagnosed with multiple giant CAAs combined with RCA-PA fistula. The patient, a 60-year-old female, presented to the emergency room because of progressive exertional chest distress and fatigue. The tra...
Published on 2019in Journal of Neuroimmunology2.83
Jingfang Lin (Sichuan University), Linmao Zheng (Sichuan University)+ 1 AuthorsZhen Hong (Sichuan University)
Abstract IgG4-related disease (IgG4-RD) is an immune-mediated condition that affects multiple organ systems with tumorlike swelling. Here, for the first time, we report a rare case of IgG4-RD that involves the cerebral parenchyma, intramedullary spinal cord and lymph nodes. The diagnosis of IgG4-RD was made based on histological features, multi organ involvement and high serum IgG4 levels. The patient responded well to glucocorticoid treatment. Our case broadens the phenotypic presentation for t...
Published on Jun 1, 2019in World Neurosurgery1.72
Stephen J. Slade (Virginia Mason Medical Center), Erin M. Bauer (Virginia Mason Medical Center)+ 1 AuthorsAmish J. Dave (Virginia Mason Medical Center)
Abstract Background Back pain is a leading reason patients seek medical attention. While musculoskeletal causes are common, rarer etiologies can present. Case Description A 50-year-old male presented with 2 months of isolated upper back pain initially suspected to be secondary to overuse muscular strain. Over the next 3 months, his pain worsened, and he developed lower extremity dysesthesias and subjective weakness despite a normal neurological exam. Non-revealing laboratory workup included norm...
Published on Mar 20, 2019in Clinical Journal of Gastroenterology
Kenji Yorita11
Estimated H-index: 11
,
Shinichi Iwamura2
Estimated H-index: 2
We present an asymptomatic case of a 79-year-old Japanese man who had a 6 mm colonic inflammatory polyp with numerous immunoglobulin G4 (IgG4)-positive plasma cells. No symptoms or abnormal laboratory data, such as changes in serum IgG4 levels, were found at the time of diagnosis or during the 1 year of follow-up thereafter. Additionally, no diffuse/localized swelling or masses were found in organs, except for colonic polyps, by abdominal computed tomography 1 year prior to the polypectomy. Infl...
Published on May 21, 2019in Heart5.08
C Perez-Garcia2
Estimated H-index: 2
(Cardiovascular Institute of the South),
Carlos Nicolás Pérez-García (Cardiovascular Institute of the South)+ 10 AuthorsDaniel Enríquez-Vázquez1
Estimated H-index: 1
(Cardiovascular Institute of the South)
Objective The incidence of aortitis in patients with thoracic aortic diseases is not well established. The aim of this study was to analyse the frequency and clinical course of patients with aortitis in a surgical series. Methods 320 consecutive patients with ascending aorta/aortic arch aneurysm or acute aortic syndrome who underwent surgery from 2012 to 2017 in a single tertiary referral hospital were retrospectively reviewed. Epidemiological data, clinical course and variables related to diagn...
View next paperHigh Serum IgG4 Concentrations in Patients with Sclerosing Pancreatitis