Reduction of serum triglyceride levels by polyunsaturated fat Studies on the mode of action and on very low density lipoprotein composition

1.(1) When isocaloric diets high in saturated fat or polyunsaturated fat were alternately fed to hyperlipidaemic and normal men, serum triglyceride was 35% lower (P < 0.001) and serum cholesterol 16% lower (P < 0.001) during the unsaturated fat diet than during saturated fat feeding. A similar response occurred in normal subjects and in patients with primary endogenous hyperglyceridaemia. 2.(2) The magnitude of the reduction of both serum...