A phase transition in a protein crystal: The example of hen lysozyme

Increasing evidence exists now to suggest that enzymes can crystallize at higher temperatures than was generally thought. Hen lysozyme is a good example, crystallizing at temperatures up to 60 °C. Moreover, it exhibits a phase transition at a precise temperature which depends on the anions bound to the enzyme. The high temperature crystals are briefly described and the influence of various factors are discussed. The high temperature form has...