Comparable constitutive expression and activity of cytochrome P450 between the lobes of the porcine liver
Abstract
Due to limited availability of human liver tissue for the study of cytochrome P450 (CYP450), porcine liver tissue has been suggested as an alternative source to prepare microsomes and hepatocytes. The porcine liver is made by four different lobes. The present study investigated the expression and activity of specific CYP450 isoforms in the four lobes, with the purpose to examine if one lobe of the porcine liver resembles the human more than...
Paper Details
Title
Comparable constitutive expression and activity of cytochrome P450 between the lobes of the porcine liver
Published Date
Oct 1, 2014
Journal
Volume
28
Issue
7
Pages
1190 - 1195
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