Cost-Effectiveness of Low-Molecular-Weight Heparin Compared with Aspirin for Prophylaxis Against Venous Thromboembolism After Total Joint Arthroplasty

There is controversy regarding the most appropriate strategy to prevent venous thromboembolism following total joint arthroplasty. Our objective was to estimate the lifetime costs, quality-adjusted life-years (QALYs), and costs per QALY gained using low-molecular-weight heparin compared with low-dose aspirin for two weeks after total knee or total hip arthroplasty in patients with no history of venous thromboembolism.We used a Markov cohort...