Antioxidant properties of aged garlic extract: an in vitro study incorporating human low density lipoprotein

Oxidation of low-density lipoprotein (LDL) has been recognized as playing an important role in the development and progression of atherosclerotic heart disease. Human LDL was isolated and challenged with a range of oxidants either in the presence or absence of AGE or its diethyl ether extract. Oxidative modification of the LDL fraction using CuSO4, 5-lipoxygenase and xanthine/xanthine oxidase was monitored by both the appearance of...