Drug pipeline in neurodegeneration based on transgenic mice models of Alzheimer's disease
Abstract
Alzheimer's disease (AD) is one of the most important neurodegenerative disorders, bringing about huge medical and social burden in the elderly worldwide. Many aspects of its pathogenesis have remained unclear and no effective treatment exists for it. Within the past 20 years, various mice models harboring AD-related human mutations have been produced. These models imitate diverse AD-related pathologies and have been used for basic and...
Paper Details
Title
Drug pipeline in neurodegeneration based on transgenic mice models of Alzheimer's disease
Published Date
Jan 1, 2013
Journal
Volume
12
Issue
1
Pages
116 - 140
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