Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers

Volume: 11, Issue: 5, Pages: 545 - 548
Published: May 1, 2014
Abstract
X-ray free-electron laser (XFEL) sources enable the use of crystallography to solve three-dimensional macromolecular structures under native conditions and without radiation damage. Results to date, however, have been limited by the challenge of deriving accurate Bragg intensities from a heterogeneous population of microcrystals, while at the same time modeling the X-ray spectrum and detector geometry. Here we present a computational approach...
Paper Details
Title
Accurate macromolecular structures using minimal measurements from X-ray free-electron lasers
Published Date
May 1, 2014
Volume
11
Issue
5
Pages
545 - 548
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