Expression and localization of NOX2 and NOX4 in primary human endothelial cells
Abstract
Reactive oxygen species (ROS) control the integrity of the vascular endothelium. Our laboratory has recently shown that transduction of human umbilical vein endothelial cells (HUVECs) with an active variant of the small GTPase Rac promotes the production of ROS, ROS-dependent activation of p38 mitogen-activated protein kinase, and loss of vascular/endothelial-cadherin-mediated cell–cell adhesion. Here we show that HUVECs express mRNAs for NOX2...
Paper Details
Title
Expression and localization of NOX2 and NOX4 in primary human endothelial cells
Published Date
Feb 10, 2005
Volume
7
Pages
308 - 317
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