Improving Protein and Proteome Coverage through Data-Independent Multiplexed Peptide Fragmentation

Volume: 9, Issue: 7, Pages: 3621 - 3637
Published: May 24, 2010
Abstract
Performance differences in protein and proteome characterization achieved by data-independent acquisition (DIA) LC/MSE and data-dependent acquisition (DDA) LC/MS/MS approaches were investigated. LC/MSE is a novel mode of generating product ion data for all coeluting precursors in parallel as opposed to LC/MS/MS where coeluting precursors must be serially fragmented one at a time. During LC/MSE analysis, alternating MS scans of “normal” and...
Paper Details
Title
Improving Protein and Proteome Coverage through Data-Independent Multiplexed Peptide Fragmentation
Published Date
May 24, 2010
Volume
9
Issue
7
Pages
3621 - 3637
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.