Transcriptional Pattern of Genes Coding for the Proteolytic System of Lactococcus lactis and Evidence for Coordinated Regulation of Key Enzymes by Peptide Supply

The transcription of 16 genes encoding 12 peptidases ( pepC, pepN, pepX, pepP, pepA, pepF2, pepDA1, pepDA2, pepQ, pepT, pepM , and pepO1 ), P I and P III proteinases ( prtP1 and prtP3 ), and three transport systems ( dtpT, dtpP, and opp-pepO1 ) of Lactococcus lactis MG1363 was analyzed in response to different environmental factors. Promoter fusions with luciferase reporter genes and/or mRNA analysis were used to study the effects of sugar...