The Tetraspanin CD9 Modulates Epidermal Growth Factor Receptor Signaling in Cancer Cells
Abstract
CD9 is a member of the tetraspanins, and has been shown to be involved in a variety of cellular activities such as migration, proliferation, and adhesion. In addition, it has been known that CD9 can associate with other proteins. Here we demonstrated the physical and functional association of CD9 with epidermal growth factor receptor (EGFR) on MKN-28 cells. Double-immunofluorescent staining and immunoprecipitation demonstrated the complex...
Paper Details
Title
The Tetraspanin CD9 Modulates Epidermal Growth Factor Receptor Signaling in Cancer Cells
Published Date
Jul 1, 2008
Volume
216
Issue
1
Pages
135 - 143
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