Reactive Astrocytes As Therapeutic Targets for CNS Disorders
Abstract
Reactive astrogliosis has long been recognized as a ubiquitous feature of CNS pathologies. Although its roles in CNS pathology are only beginning to be defined, genetic tools are enabling molecular dissection of the functions and mechanisms of reactive astrogliosis in vivo. It is now clear that reactive astrogliosis is not simply an all-or-nothing phenomenon but, rather, is a finely gradated continuum of molecular, cellular, and functional...
Paper Details
Title
Reactive Astrocytes As Therapeutic Targets for CNS Disorders
Published Date
Oct 1, 2010
Journal
Volume
7
Issue
4
Pages
494 - 506
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