Altered fibrin clot structure/function in patients with idiopathic venous thromboembolism and in their relatives
Abstract
We tested the hypothesis that fibrin structure/function is unfavorably altered in patients after idiopathic venous thromboembolism (VTE) and their relatives. Ex vivo plasma fibrin clot permeability, turbidimetry, and efficiency of fibrinolysis were investigated in 100 patients with first-ever VTE, including 34 with pulmonary embolism (PE), 100 first-degree relatives, and 100 asymptomatic controls with no history of thrombotic events. Known...
Paper Details
Title
Altered fibrin clot structure/function in patients with idiopathic venous thromboembolism and in their relatives
Published Date
Nov 5, 2009
Journal
Volume
114
Issue
19
Pages
4272 - 4278
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