CARD15 Mutations in Patients With Crohn's Disease in a Homogeneous Spanish Population

OBJECTIVES Three mutations in CARD15 have been repeatedly shown to be involved in Crohn's disease susceptibility, mainly in Caucasian individuals. However, those findings were not replicated in all populations studied so far. In this work, we studied the role of CARD15 mutations in a relatively homogeneous population from the Northwest of Spain, Galicia. METHODS One hundred and sixty-five patients with Crohn's disease and a similar number of...