Noncanonical Role of the 9-1-1 Clamp in the Error-Free DNA Damage Tolerance Pathway
Abstract
Damaged DNA is an obstacle during DNA replication and a cause of genome instability and cancer. To bypass this problem, eukaryotes activate DNA damage tolerance (DDT) pathways that involve ubiquitylation of the DNA polymerase clamp proliferating cell nuclear antigen (PCNA). Monoubiquitylation of PCNA mediates an error-prone pathway by recruiting translesion polymerases, whereas polyubiquitylation activates an error-free pathway that utilizes...
Paper Details
Title
Noncanonical Role of the 9-1-1 Clamp in the Error-Free DNA Damage Tolerance Pathway
Published Date
Feb 1, 2013
Journal
Volume
49
Issue
3
Pages
536 - 546
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History