p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity
Abstract
Proper regulation of white and brown adipogenic differentiation is important for maintaining an organism's metabolic profile in a homeostatic state. The recent observations showing that the p53 tumor suppressor plays a role in metabolism raise the question of whether it is involved in the regulation of white and brown adipocyte differentiation. By using several in vitro models, representing various stages of white adipocyte differentiation, we...
Paper Details
Title
p53 is required for brown adipogenic differentiation and has a protective role against diet-induced obesity
Published Date
Feb 15, 2013
Journal
Volume
20
Issue
5
Pages
774 - 783
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