Consequences of genomic diversity in Mycobacterium tuberculosis
Abstract
The causative agent of human tuberculosis, Mycobacterium tuberculosis complex (MTBC), comprises seven phylogenetically distinct lineages associated with different geographical regions. Here we review the latest findings on the nature and amount of genomic diversity within and between MTBC lineages. We then review recent evidence for the effect of this genomic diversity on mycobacterial phenotypes measured experimentally and in clinical settings....
Paper Details
Title
Consequences of genomic diversity in Mycobacterium tuberculosis
Published Date
Dec 1, 2014
Journal
Volume
26
Issue
6
Pages
431 - 444
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