Pathogenesis of mild parkinsonian signs in aging

In their recent study on the evolution of mild parkinson signs (MPS) in aging, Mahoney et al. [4], in a cohort of 210 healthy older adults, none of them demented, MPS were observed in 45 %, 38 % of whom were transient (mean age 75.8 ± 7.37 years), while 61 % were persistent (mean age 79.8 ± 7.15 years). For the onset of MPS vascular mechanisms due to cardiovascular disease were suggested, and probably neurodegenerative mechanisms for the...