Escherichia�coli ?-haemolysin induces focal leaks in colonic epithelium: a novel mechanism of bacterial translocation
Abstract
Extraintestinal pathogenic Escherichia coli (ExPEC) are usually harmless colonizer of the intestinal microflora. However, they are capable to translocate and cause life-threatening disease. Translocation of ExPEC isolates was quantified in colonic monolayers. Transepithelial resistance (Rt) was monitored and local changes in conductivity analysed with conductance scanning. Confocal microscopy visualized the translocation route. Corroboratory...
Paper Details
Title
Escherichia�coli ?-haemolysin induces focal leaks in colonic epithelium: a novel mechanism of bacterial translocation
Published Date
Oct 1, 2007
Journal
Volume
9
Issue
10
Pages
2530 - 2540
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