Clinical features of thyroid autoimmunity are associated with thyroiditis on histology and are not predictive of malignancy in 570 patients with indeterminate nodules on cytology who had a thyroidectomy

Summary Background The relationship between thyroid autoimmunity and cancer is still uncertain. Patients We approached this issue in 570 consecutive patients submitted to thyroidectomy for an indeterminate nodule on cytology. Thyroid autoimmunity was defined as positivity of circulating thyroid autoantibodies (TAb), autoimmune hypo‐ or hyperthyroidism, thyroid hypoechogenicity on ultrasound, and lymphocytic infiltration on histology. Results TAb...