Dominance of the strongest: Inflammatory cytokines versus glucocorticoids
Abstract
Pro-inflammatory cytokines are involved in the pathogenesis of many inflammatory diseases, and the excessive expression of many of them is normally counteracted by glucocorticoids (GCs), which are steroids that bind to the glucocorticoid receptor (GR). Hence, GCs are potent inhibitors of inflammation, and they are widely used to treat inflammatory diseases, such as asthma, rheumatoid arthritis and inflammatory bowel disease. However, despite the...
Paper Details
Title
Dominance of the strongest: Inflammatory cytokines versus glucocorticoids
Published Date
Feb 1, 2014
Volume
25
Issue
1
Pages
21 - 33
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