Association analysis of polymorphisms in the upstream region of the human dopamine D4 receptor gene in schizophrenia
Abstract
Several studies have suggested that the transcriptional activity of the DRD4 gene may exert an important role in susceptibility to schizophrenia. To address this issue, we studied the association of schizophrenia and polymorphisms including -616C>G, -603T>del, -602G>del, 600G>C, -521C>T, -376C>T and a 120 bp tandem duplication polymorphism (120 bp repeat) in 1.2 kb upstream from the initiation codon in the promoter region of the DRD4 gene with...
Paper Details
Title
Association analysis of polymorphisms in the upstream region of the human dopamine D4 receptor gene in schizophrenia
Published Date
Dec 1, 2003
Journal
Volume
65
Issue
1
Pages
9 - 14
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