Neural stem cells and regulation of cell number
Abstract
Normal CNS development involves the sequential differentiation of multipotent stem cells. Alteration of the numbers of stem cells, their self-renewal ability, or their proliferative capacity will have major effects on the appropriate development of the nervous system. In this review, we discuss different mechanisms that regulate neural stem cell differentiation. Proliferation signals and cell cycle regulators may regulate cell kinetics or total...
Paper Details
Title
Neural stem cells and regulation of cell number
Published Date
Jan 1, 2002
Journal
Volume
66
Issue
1
Pages
1 - 18
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