Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features
Abstract
KRAS-mutated carcinomas comprise 35-40% of all colorectal carcinomas but little is known about their characteristics. The aim of this study was to examine the pathological and molecular features of KRAS-mutated colorectal carcinomas and to compare them with other carcinoma subgroups. KRAS mutation testing was performed in 776 incident tumors from the Melbourne Collaborative Cohort Study. O(6)-methylguanine DNA methyltransferase (MGMT) status was...
Paper Details
Title
Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features
Published Date
Jun 1, 2013
Journal
Volume
26
Issue
6
Pages
825 - 834
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