A simple and rapid method for the permethylation of carbohydrates

Volume: 131, Issue: 2, Pages: 209 - 217
Published: Aug 15, 1984
Abstract
null null As a result of a study of the permethylation of sugars in such dipolar aprotic solvents as methyl sulphoxide, the hitherto accepted role of the CH3SOCH−2 anion is questioned. The HO− and H− ions appear to be the effective basic agents in these methylation reactions. This conclusion suggested a new method for the permethylation of sugars involving methyl iodide, a solid base (NaOH, KOH, or tert-BuOH/NaOH), and methyl sulphoxide....
Paper Details
Title
A simple and rapid method for the permethylation of carbohydrates
Published Date
Aug 15, 1984
Volume
131
Issue
2
Pages
209 - 217
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