T-bet: a bridge between innate and adaptive immunity
Abstract
Originally described over a decade ago as a T cell transcription factor regulating T helper 1 cell lineage commitment, T-bet is now recognized as having an important role in many cells of the adaptive and innate immune system. T-bet has a fundamental role in coordinating type 1 immune responses by controlling a network of genetic programmes that regulate the development of certain immune cells and the effector functions of others. Many of these...
Paper Details
Title
T-bet: a bridge between innate and adaptive immunity
Published Date
Oct 11, 2013
Journal
Volume
13
Issue
11
Pages
777 - 789
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Notes
History