Interactions of Aspergillus fumigatus with endothelial cells: internalization, injury, and stimulation of tissue factor activity

Blood20.30
Volume: 103, Issue: 6, Pages: 2143 - 2149
Published: Mar 15, 2004
Abstract
Invasive aspergillosis causes significant mortality among patients with hematologic malignancies. This infection is characterized by vascular invasion and thrombosis. To study the pathogenesis of invasive aspergillosis, we investigated the interactions of Aspergillus fumigatus conidia and hyphae with endothelial cells in vitro. We found that both forms of the organism induced endothelial cell microfilament rearrangement and subsequent...
Paper Details
Title
Interactions of Aspergillus fumigatus with endothelial cells: internalization, injury, and stimulation of tissue factor activity
Published Date
Mar 15, 2004
Journal
Volume
103
Issue
6
Pages
2143 - 2149
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