Effects of Dehydroepiandrosterone on Gluconeogenic Enzymes and Glucose Uptake in Human Hepatoma Cell Line, HepG2
Abstract
Dehydroepiandrosterone (DHEA), the most abundant human adrenal steroid, improves insulin sensitivity and obesity in human and model animals. In a previous study, we reported that orally administered DHEA suppresses the elevated activities of hepatic gluconeogenic enzymes like glucose-6-phosphatase (G6Pase) in C57BL/KsJ-db/db mice (Aoki K, Saito T, Satoh S, Mukasa K, Kaneshiro M, Kawasaki S, Okamura A, Sekihara H (1999) Diabetes 48: 1579–1585)....
Paper Details
Title
Effects of Dehydroepiandrosterone on Gluconeogenic Enzymes and Glucose Uptake in Human Hepatoma Cell Line, HepG2
Published Date
Jan 1, 2005
Journal
Volume
52
Issue
6
Pages
727 - 733
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