Reinventing the ACE inhibitors: some old and new implications of ACE inhibition
Abstract
Since their inception, angiotensin-converting enzyme (ACE) inhibitors have been used as first-line therapy for the treatment of cardiovascular and renal diseases. They restore the balance between the vasoconstrictive salt-retentive and hypertrophy-causing peptide angiotensin II (Ang II) and bradykinin, a vasodilatory and natriuretic peptide. As ACE is a promiscuous enzyme, ACE inhibitors alter the metabolism of a number of other vasoactive...
Paper Details
Title
Reinventing the ACE inhibitors: some old and new implications of ACE inhibition
Published Date
Nov 13, 2009
Journal
Volume
33
Issue
1
Pages
11 - 21
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