Role of genetic variation in insulin-like growth factor 1 receptor on insulin resistance and arterial hypertension

Objective To perform a two-stage study to explore the role of gene variants in the risk of insulin resistance and arterial hypertension. Methods and results The selection of variants was performed by a first stage of in-silico analysis of the original genome-wide association data sets on genes involved in metabolic syndrome components, granted by the Diabetes Genetics Initiative and the Wellcome Trust Case–Control Consortium. We started by...