Reduced uptake and enhanced release of cadmium in cadmium-resistant metallothionein null fibroblasts.
Abstract
null null Metallothionein (MT) is known to play a predominant role in the protection of cells from cadmium (Cd) toxicity. To investigate other factors involved in Cd resistance, we established Cd-resistant cell lines from simian virus 40-transformed MT null fibroblasts. Cd-resistant MT null cells, Cd-rA7 and Cd-rB5, developed approximately 10-fold resistance to Cd compared to parental cells, but showed no cross-resistance to Zn, Cu, Hg, Ni, As,...
Paper Details
Title
Reduced uptake and enhanced release of cadmium in cadmium-resistant metallothionein null fibroblasts.
Published Date
Aug 27, 1999
Journal
Volume
65
Issue
14
Pages
177 - 182
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