Intestinal mucosa permeability following oral insulin delivery using core shell corona nanolipoparticles
Abstract
Chitosan nanoparticles (NC) have excellent capacity for protein entrapment, favorable epithelial permeability, and are regarded as promising nanocarriers for oral protein delivery. Herein, we designed and evaluated a class of core shell corona nanolipoparticles (CSC) to further improve the absorption through enhanced intestinal mucus penetration. CSC contains chitosan nanoparticles as a core component and pluronic F127-lipid vesicles as a shell...
Paper Details
Title
Intestinal mucosa permeability following oral insulin delivery using core shell corona nanolipoparticles
Published Date
Dec 1, 2013
Journal
Volume
34
Issue
37
Pages
9678 - 9687
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History