Traditional uses and medicinal potential of Cordyceps sinensis of Sikkim.

Published on Jan 1, 2011in Journal of Ayurveda and Integrative Medicine
· DOI :10.4103/0975-9476.78183
Ashok Kumar Panda4
Estimated H-index: 4
,
Kailash Chandra Swain1
Estimated H-index: 1
(Manipal University)
Abstract
Cordyceps sinensis has been described as a medicine in old Chinese medical books and Tibetan medicine. It is a rare combination of a caterpillar and a fungus and found at altitudes above 4500m in Sikkim. Traditional healers and local people of North Sikkim recommend the mushroom, i.e., Yarsa gumba, Keera jhar (C. sinensis ) for all diseases either as a single drug or combined with other herbs. The present study was undertaken to collect information regarding the traditional uses of cordyceps in Sikkim. It was found that most local folk healers/traditional healers use cordyceps for the treatment of 21 ailments. A modern literature search was carried out to assess whether the curative effects are valid or just blind faith of local people. Chemical constituents of cordyceps are given and pharmacological and biological studies reviewed. More mechanism-based and disease-oriented clinical studies are recommended.
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  • Citations (29)
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Cited By29
Kshipra Misra7
Estimated H-index: 7
(Defence Institute of Physiology and Allied Sciences),
Rajkumar Tulsawani7
Estimated H-index: 7
(Defence Institute of Physiology and Allied Sciences)
+ 2 AuthorsGerda E. Morlock (University of Hohenheim)
Kshipra Misra7
Estimated H-index: 7
(Defence Institute of Physiology and Allied Sciences),
Rajkumar Tulsawani7
Estimated H-index: 7
(Defence Institute of Physiology and Allied Sciences)
+ 2 AuthorsGertrud E. Morlock28
Estimated H-index: 28
(University of Giessen)
The high-performance thin-layer chromatographic (HPTLC) profiling of sugars, sugar alcohols, amino acids, flavonoids, and phenolic acids, as well as bioactive and antioxidative compounds, is described for the first time in aqueous and hydroalcoholic extracts of some Indian herbs, namely, Hippophae rhamnoides, Valeriana wallichii, Triticum aestivum, and the fungus Cordyceps sinensis, all known for their natural performance enhancement capacity. For the analysis of bioactive compounds such as flav...
11 Citations Source Cite
Hui-Chen Lo10
Estimated H-index: 10
(Fu Jen Catholic University),
Chienyan Hsieh1
Estimated H-index: 1
(National Kaohsiung Normal University)
+ 1 AuthorsTai-Hao Hsu11
Estimated H-index: 11
ABSTRACT The caterpillar fungus Ophiocordyceps sinensis (syn. † Cordyceps sinensis ), which was originally used in traditional Tibetan and Chinese medicine, is called either “yartsa gunbu” or “DongChongXiaCao (冬蟲夏草 Dōng Chong Xia Cǎo)” (“winter worm-summer grass”), respectively. The extremely high price of DongChongXiaCao, approximately USD $20,000 to 40,000 per kg, has led to it being regarded as “soft gold” in China. The multi-fungi hypothesis has been proposed for DongChongXiaCao; however, Hi...
36 Citations Source Cite
Published on Oct 1, 2015in International Journal of Molecular Medicine 2.78
Yingxin Zou3
Estimated H-index: 3
,
Yuxiang Liu1
Estimated H-index: 1
+ 4 AuthorsZe-Sheng Zhang3
Estimated H-index: 3
(Tianjin University of Science and Technology)
This study investigated the effect of Cordyceps sinensis oral liquid (CSOL) on the lifespan of Drosophila melanogaster (fruit fly). Following the lifelong treatment of fruit flies with CSOL, lifespan was examined. The activity of copper-zinc-containing superoxide dismutase 1 (SOD1), manganese-containing superoxide dismutase 2 (SOD2) and catalase (CAT), as well as the lipofuscin (LF) content were determined. The mRNA levels of SOD1, SOD2 and CAT were quantified by qPCR. Hydrogen peroxide (H2O2) a...
7 Citations Source Cite
Published on Mar 3, 2016in Mitochondrial DNA 0.92
Linping Wang1
Estimated H-index: 1
(Beijing Normal University),
Jiayue Xu1
Estimated H-index: 1
(Beijing Institute of Genomics)
+ 5 AuthorsChengqiang Feng1
Estimated H-index: 1
(Beijing Normal University)
AbtractPaecilomyces hepiali, belonging to the Eurotiales order Ascomycota, is an endoparasitic fungus that commonly exists in the natural Cordyceps sinensis anamorph stage. Here, we report the complete mitochondrial DNA sequences of P. hepiali for the first time. The genome is 24,245 bp in length, encoding 15 protein-coding genes (PCGs), 2 rRNA genes, 25 tRNA genes and 3 homing endonucleases. The overall AT composition is 73.37% and the average AT content of PCG, rRNA, tRNA and non-coding region...
1 Citations Source Cite
Yan Li4
Estimated H-index: 4
,
Ji Zhang12
Estimated H-index: 12
+ 3 AuthorsYuan-Zhong Wang13
Estimated H-index: 13
The fungus species Wolfiporia extensa has a long history of medicinal usage and has also been commercially used to formulate nutraceuticals and functional foods in certain Asian countries. In the present study, a practical and promising method has been developed to discriminate the dried sclerotium of W. extensa collected from different geographical sites based on UV spectroscopy together with chemometrics methods. Characteristic fingerprint of low polar constituents of sample extracts that orig...
9 Citations Source Cite
Published on Apr 1, 2014in Journal of Ocean University of China 0.57
Shiwei Hu7
Estimated H-index: 7
(Ocean University of China),
Jingfeng Wang23
Estimated H-index: 23
(Ocean University of China)
+ 3 AuthorsChanghu Xue34
Estimated H-index: 34
(Ocean University of China)
Sea cucumber and cordyceps sinensis are used as both food and traditional medicines in Asia. This study was carried out in order to investigate the hpyerglycemic effect of a mixture of sea cucumber (Apostichopus japonicas) and cordyceps sinensis (Cordyceps militaris) (SCC) in diabetic rat and explore the mechanism underlining such an effect. The diabetic model rat was induced with intraperitoneal injection of streptozotocin (STZ). The diabetic model rats were randomly divided into control group ...
1 Citations Source Cite
Published on Jan 1, 2014in Journal of Ethnopharmacology 3.12
Seon Beom Kim10
Estimated H-index: 10
(Chungbuk National University),
Byeongwoo Ahn15
Estimated H-index: 15
(Chungbuk National University)
+ 6 AuthorsMi Kyeong Lee20
Estimated H-index: 20
(Chungbuk National University)
Abstract Ethnopharmacological relevance Cordyceps species which is well-known as ‘winter worm summer grass’ has long been used as tonics and stimulants to enhance energy, exhibiting a potential for energy metabolism. Clinical trials have suggested their beneficial effect on lipid metabolic disorders such as hyperlipidemia. Materials and methods The effect of Cordyceps militaris on metabolic parameters was investigated using C58BL/6J mice induced by high-fat diet (HFD). The effect was first deter...
25 Citations Source Cite
Published on Jan 1, 2013in International Journal of Medicinal Mushrooms 1.21
Kai Yue7
Estimated H-index: 7
(Sichuan Agricultural University),
Meng Ye2
Estimated H-index: 2
(Sichuan Agricultural University)
+ 1 AuthorsZuji Zhou2
Estimated H-index: 2
(Sichuan Agricultural University)
6 Citations Source Cite
Published on Dec 1, 2015in Pastoralism
Kesang Wangchuk1
Estimated H-index: 1
,
Jigme Wangdi1
Estimated H-index: 1
Yak farming is the main livelihood source for the high altitude communities in the eastern Himalaya. With increasing access to modern facilities, market opportunities and changes in the legal framework, pastoral systems in the Himalaya are undergoing an unprecedented change. Questionnaire-based qualitative surveys were conducted in five villages of northern Bhutan, to understand how the recent changes in the legal framework for Cordyceps (known as caterpillar fungus) collection have caused speci...
6 Citations Source Cite