The Transcript-centric Mutations in Human Genomes
Abstract
Since the human genome is mostly transcribed, genetic variations must exhibit sequence signatures reflecting the relationship between transcription processes and chromosomal structures as we have observed in unicellular organisms. In this study, a set of 646 ubiquitous expression-invariable genes (EIGs) which are present in germline cells were defined and examined based on RNA-sequencing data from multiple high-throughput transcriptomic data. We...
Paper Details
Title
The Transcript-centric Mutations in Human Genomes
Published Date
Feb 1, 2012
Volume
10
Issue
1
Pages
11 - 22
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