Regulation of systemic energy homeostasis by serotonin in adipose tissues
Abstract
Central serotonin (5-HT) is an anorexigenic neurotransmitter in the brain. However, accumulating evidence suggests peripheral 5-HT may affect organismal energy homeostasis. Here we show 5-HT regulates white and brown adipose tissue function. Pharmacological inhibition of 5-HT synthesis leads to inhibition of lipogenesis in epididymal white adipose tissue (WAT), induction of browning in inguinal WAT and activation of adaptive thermogenesis in...
Paper Details
Title
Regulation of systemic energy homeostasis by serotonin in adipose tissues
Published Date
Apr 13, 2015
Journal
Volume
6
Issue
1
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