A not cytotoxic nickel concentration alters the expression of neuronal differentiation markers in NT2 cells
Abstract
Nickel, a known occupational/environmental hazard, may cross the placenta and reach appreciable concentrations in various fetal organs, including the brain. The aim of this study was to investigate whether nickel interferes with the process of neuronal differentiation. Following a 4 week treatment with retinoic acid (10μM), the human teratocarcinoma-derived NTera2/D1 cell line (NT2 cells) terminally differentiate into neurons which recapitulate...
Paper Details
Title
A not cytotoxic nickel concentration alters the expression of neuronal differentiation markers in NT2 cells
Published Date
Mar 1, 2015
Journal
Volume
47
Pages
47 - 53
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