Synthesis and characterization of glycoconjugate tin(IV) complexes: In vitro DNA binding studies, cytotoxicity, and cell death

Volume: 696, Issue: 8, Pages: 1600 - 1608
Published: Apr 1, 2011
Abstract
New glycosyl derived ligand and its complexes, with SnCl4·5H2O (1) and (CH3)2SnCl2 (2) were synthesized and characterized by spectroscopic (IR, 1H, 13C, and 119Sn NMR, UV–vis, ESI-MS) and analytical methods. Interaction studies of 1 and 2 with CT DNA were studied by using various biophysical techniques, which showed high binding affinity of 2 with CT DNA. In vitro cytotoxicity of complexes 1 and 2 were evaluated against different human cancer...
Paper Details
Title
Synthesis and characterization of glycoconjugate tin(IV) complexes: In vitro DNA binding studies, cytotoxicity, and cell death
Published Date
Apr 1, 2011
Volume
696
Issue
8
Pages
1600 - 1608
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