Altered white matter microstructure is associated with social cognition and psychotic symptoms in 22q11.2 microdeletion syndrome

Volume: 8
Published: Nov 11, 2014
Abstract
22q11.2 Microdeletion Syndrome (22q11DS) is a highly penetrant genetic mutation associated with a significantly increased risk for psychosis. Aberrant neurodevelopment may lead to inappropriate neural circuit formation and cerebral dysconnectivity in 22q11DS, which may contribute to symptom development. Here we examined: 1) differences between 22q11DS participants and typically developing controls in diffusion tensor imaging (DTI) measures...
Paper Details
Title
Altered white matter microstructure is associated with social cognition and psychotic symptoms in 22q11.2 microdeletion syndrome
Published Date
Nov 11, 2014
Volume
8
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