Synthesis and biological applications of ionic triphenyltin(iv) chloride carboxylate complexes with exceptionally high cytotoxicity
Abstract
The reaction of N-phthaloylglycine (P-GlyH), N-phthaloyl-l-alanine (P-AlaH), and 1,2,4-benzenetricarboxylic 1,2-anhydride (BTCH) with triethylamine led to the formation of the corresponding ammonium salts[NHEt3][P-Gly] (1), [NHEt3][P-Ala] (2) and [NHEt3][BTC] (3) in very high yields. The subsequent reaction of 1–3 with triphenyltin(iv) chloride (1 : 1) yielded the compounds [NHEt3][SnPh3Cl(P-Gly)] (4), [NHEt3][SnPh3Cl(P-Ala)] (5), and...
Paper Details
Title
Synthesis and biological applications of ionic triphenyltin(iv) chloride carboxylate complexes with exceptionally high cytotoxicity
Published Date
Jan 1, 2010
Journal
Volume
2
Issue
6
Pages
419 - 419
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