Review paper

Novel insight into mechanisms of cholestatic liver injury

Volume: 18, Issue: 36, Pages: 4985 - 4985
Published: Jan 1, 2012
Abstract
Cholestasis results in a buildup of bile acids in serum and in hepatocytes. Early studies into the mechanisms of cholestatic liver injury strongly implicated bile acid-induced apoptosis as the major cause of hepatocellular injury. Recent work has focused both on the role of bile acids in cell signaling as well as the role of sterile inflammation in the pathophysiology. Advances in modern analytical methodology have allowed for more accurate...
Paper Details
Title
Novel insight into mechanisms of cholestatic liver injury
Published Date
Jan 1, 2012
Volume
18
Issue
36
Pages
4985 - 4985
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