The Integrin β1 Subunit Regulates Paracellular Permeability of Kidney Proximal Tubule Cells
Abstract
Epithelial cells lining the gastrointestinal tract and kidney have different abilities to facilitate paracellular and transcellular transport of water and solutes. In the kidney, the proximal tubule allows both transcellular and paracellular transport, while the collecting duct primarily facilitates transcellular transport. The claudins and E-cadherin are major structural and functional components regulating paracellular transport. In this study...
Paper Details
Title
The Integrin β1 Subunit Regulates Paracellular Permeability of Kidney Proximal Tubule Cells
Published Date
Mar 1, 2014
Volume
289
Issue
12
Pages
8532 - 8544
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