microRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress

Volume: 4, Issue: 4, Pages: e604 - e604
Published: Apr 18, 2013
Abstract
Sustained endoplasmic reticulum (ER) stress has been linked to cell death and the pathogenesis of many liver diseases, including toxic liver, cholestasis, and infectious liver disease. The cellular pathways that attenuate hepatic ER stress have been the focus of many recent studies, but the role of microRNAs (miRNA) in this process remains unknown. Here, we report that one of the most abundant miRNAs in hepatocytes, miR-199a-5p, was elevated in...
Paper Details
Title
microRNA-199a-5p protects hepatocytes from bile acid-induced sustained endoplasmic reticulum stress
Published Date
Apr 18, 2013
Volume
4
Issue
4
Pages
e604 - e604
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