Match!

Identification of Trans-β-santalol and epi-cis-β-santalol in east indian sandalwood oil☆

Published on Jan 1, 1981in Phytochemistry2.905
· DOI :10.1016/0031-9422(81)83047-6
Philip A. Christenson4
Estimated H-index: 4
,
Norman Secord1
Estimated H-index: 1
,
Brian J. Willis3
Estimated H-index: 3
Sources
Abstract
Abstract An analysis of East Indian sandalwood oil ( Santalum album ) has resulted in the isolation and identification of trans -β-santalol and epi-cis -β- santalol.
  • References (2)
  • Citations (21)
📖 Papers frequently viewed together
29 Citations
58 Citations
59 Citations
78% of Scinapse members use related papers. After signing in, all features are FREE.
References2
Newest
#1Edouard DemoleH-Index: 17
#2Cécile DemoleH-Index: 3
Last. Paul EnggistH-Index: 11
view all 3 authors...
58 CitationsSource
#1E. J. CoreyH-Index: 126
#2Kazuo AchiwaH-Index: 6
Last. Kazuo AchiwaH-Index: 31
view all 2 authors...
73 CitationsSource
Cited By21
Newest
#1Rashmi Saxena PalH-Index: 2
#2Yogendra PalH-Index: 2
Last. Ankita WalH-Index: 6
view all 5 authors...
Source
#1Yueya Zhang (CAS: Chinese Academy of Sciences)H-Index: 3
#2Haifeng Yan (CAS: Chinese Academy of Sciences)H-Index: 2
Last. Guohua Ma (CAS: Chinese Academy of Sciences)H-Index: 14
view all 7 authors...
1 CitationsSource
#1Tae Hoon Kim (Okayama University)H-Index: 5
#2Tsutomu Hatano (Okayama University)H-Index: 55
Last. Hideyuki Ito (Okayama Prefectural University)H-Index: 42
view all 7 authors...
In our continuing study on a survey of biologically active natural products from heartwood of Santalum album (Southwest Indian origin), we newly found potent fish toxic activity of an n-hexane soluble extract upon primary screening using killifish (medaka) and characterized α-santalol and β-santalol as the active components. The toxicity (median tolerance limit (TLm) after 24 h at 1.9 ppm) of α-santalol was comparable with that of a positive control, inulavosin (TLm after 24 h at 1.3 ppm). These...
1 CitationsSource
#1Brigette Lee (UTSA: University of Texas at San Antonio)H-Index: 1
#2Jonathan Bohmann (SwRI: Southwest Research Institute)H-Index: 5
Last. April L. RisingerH-Index: 16
view all 5 authors...
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide, with no major advancements in treatment over the past 40 years. The current study explores the biological effects of East Indian sandalwood oil (EISO) and its two major constituents, α- and β-santalol, against a variety of HNSCC lines. All three agents exhibited cytotoxic effects and caused accumulation of cells in the G2/M phases of the cell cycle. Additionally, treatment with these agents caused formation ...
8 CitationsSource
#1M. Sharma (Vancouver General Hospital)H-Index: 1
#2Corey LevensonH-Index: 3
Last. Michael E. Cox (UBC: University of British Columbia)H-Index: 27
view all 7 authors...
Medicinally, sandalwood oil (SO) has been attributed with antiinflammatory properties; however, mechanism(s) for this activity have not been elucidated. To examine how SOs affect inflammation, cytokine antibody arrays and enzyme-linked immunosorbent assays were used to assess changes in production of cytokines and chemokines by co-cultured human dermal fibroblasts and neo-epidermal keratinocytes exposed to lipopolysaccharides and SOs from Western Australian and East Indian sandalwood trees or to...
6 CitationsSource
#1Maria L. Diaz-Chavez (UBC: University of British Columbia)H-Index: 2
#2Jessie Moniodis (UWA: University of Western Australia)H-Index: 4
Last. Jörg Bohlmann (UBC: University of British Columbia)H-Index: 62
view all 10 authors...
Sandalwood oil is one of the world’s most highly prized essential oils, appearing in many high-end perfumes and fragrances. Extracted from the mature heartwood of several Santalum species, sandalwood oil is comprised mainly of sesquiterpene olefins and alcohols. Four sesquiterpenols, α-, β-, and epi-β-santalol and α-exo-bergamotol, make up approximately 90% of the oil of Santalum album. These compounds are the hydroxylated analogues of α-, β-, and epi-β-santalene and α-exo-bergamotene. By mining...
52 CitationsSource
#1Pankaj P. Daramwar (CSIR: Council of Scientific and Industrial Research)H-Index: 3
#2Prabhakar Lal Srivastava (CSIR: Council of Scientific and Industrial Research)H-Index: 5
Last. Hirekodathakallu V. Thulasiram (CSIR: Council of Scientific and Industrial Research)H-Index: 18
view all 4 authors...
The major sesquiterpene constituents of East-Indian sandalwood oil (Z)-α- and (Z)-β-santalols have shown to be responsible for most of the biological activities and organoleptic properties of sandalwood oil. The work reported here describes the strategic use of medium pressure liquid chromatography (MPLC) for the separation of both α- and β-santalenes and (Z)-α- and (Z)-β-santalols. Silver nitrate impregnated silica gel was used as the stationary phase in MPLC for quantitative separation of α- a...
15 CitationsSource
The East Indian sandalwood tree yields the costliest heartwood and essential oil that are used in traditional medicine, aromatherapy and in cosmetic and fragrance industries. Steam distillation is the traditional method employed for extraction of the sesquiterpenoid rich essential oil from chips of matured heartwood. However, there is no information available on the comparative extractability of sesquiterpenoids when different solvents are employed. Thus we used four different solvents to extrac...
6 Citations
#1Nicolas Baldovini (University of Nice Sophia Antipolis)H-Index: 14
#2Céline Delasalle (University of Nice Sophia Antipolis)H-Index: 2
Last. Daniel JoulainH-Index: 15
view all 3 authors...
A comprehensive review is presented on the constituents of the heartwood from fragrant sandalwood species, including Santalum album, S. spicatum and S. austrocaledonicum, which are important raw materials in the fragrance industry, and S. insulare, a closely related species. Analytical aspects are discussed in detail, both on qualitative and quantitative standpoints, and sensory properties are also reviewed. It is shown that more than 230 constituents have been identified so far in the heartwood...
41 CitationsSource
6 CitationsSource