A toxin-antitoxin module as a target for antimicrobial development.
Abstract
null null The emergence and spread of pathogenic bacteria that have become resistant to multiple antibiotics through lateral gene transfer have created the need of novel antimicrobials. Toxin–antitoxin (TA) modules, which have been implicated in plasmid maintenance and stress management, are ubiquitous among plasmids from vancomycin or methicillin resistant bacteria. In the Streptococcus pyogenes pSM19035-encoded TA loci, the labile e antitoxin...
Paper Details
Title
A toxin-antitoxin module as a target for antimicrobial development.
Published Date
Jan 1, 2010
Journal
Volume
63
Issue
1
Pages
31 - 39
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History