On the conformation of the hen egg-white lysozyme molecule

Crystals of hen egg-white lysozyme, grown at pH 4.7 (Alderton & Fevold 1946), are tetragonal with a = b = 79.1 Å, c = 37.9 Å, space group P 4 3 2 1 2 (Palmer, Ballantyre & Galvin 1948; Blake, Fenn, North, Phillips & Poljak 1962). Each of the eight asymmetric units in the cell comprises a single lysozyme molecule, molecular weight about 14 600, together with 1 M sodium chloride solution which constitutes some 33.5% of the weight of...